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The transcription factor HIF-1α is essential for a cell’s response to low oxygen conditions. Carbonaro et al. demonstrate that production of HIF-1α protein is regulated by dynamic microtubules and that microtubule-targeting drugs shift HIF-1α mRNA into cytoplasmic P-bodies, where its translation is repressed by miRNAs. This biosights episode presents the paper by Carbonaro et al. from the January 10, 2011, issue of The Journal of Cell Biology, and includes an interview with authors Marisa Carbonaro and Paraskevi Giannakakou (Weill Cornell Medical College, New York, NY). Produced by Caitlin Sedwick and Ben Short.
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Video Length: 426
Date Found: January 26, 2011
Date Produced: January 24, 2011
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July 16, 2011
Atlanta Skepticamp 2011 Sessions Released and distributed under the Creative Commons BY-NC-SA 3.0 United States license You are free to: Share — to copy, distribute and transmit the work Remix — to adapt the work Under the following conditions: Attribution — You must attribute the work ...
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July 16, 2011
You will learn during this hour presentation the basics of ALS, the preclinical process of drug development using small molecules, biologics and gene therapies to slow it down as well as the clinical trial stages.  Several real world examples from the lab and clinic are ...
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July 16, 2011
A frank discussion with the CDC staff in charge of the registry’s design, execution, and data interpretation.  Hosted by Steve Perrin, CEO of ALS TDI, this 90 minute conversation offers more details about the National ALS Registry than previously discussed.
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July 16, 2011
Dennis Hermesch, a professional service veterinarian with Novartis Animal Health, discusses why BVD can be difficult to control in a dairy herd and tips for building a vaccine protocol to provide coverage against the major clinical isolate of most BVD outbreaks.
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July 16, 2011
University of Toronto Physics professor Robert K. Logan on The Origin and Evolution of Language and the Emergence of Concepts
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