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The groundbreaking introduction of the tyrosine kinase inhibitor (TKI) imatinib as a treatment for chronic myeloid leukaemia (CML) has been followed by the introduction of further second and third generation TKIs. The panel discuss how TKIs act, the effect they have on patients in terms of their benefit and their toxicity profile, the importance of patients strictly complying with treatment regimens and consider the possibility of a cure for CML.A number of second and third generation TKIs have emerged in recent clinical trials and the panel explain why there has been such a need to develop numerous drugs to combat CML and consider what factors clinicians and patients should take into account when deciding which treatment to adopt.
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Video Length: 0
Date Found: February 21, 2011
Date Produced:
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 www.ecancer.tv |
March 01, 2011
Prof Mathias Rummel discusses his research demonstrating the efficacy of bendamustine plus rituximab as a treatment for mantle cell lymphomas (MCL). Following the results presented at ASH 2009 revealing the superiority of bendamustine plus rituximab over CHOP plus rituximab as first line ...
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 www.ecancer.tv |
March 01, 2011
The panel discuss how the results of recent clinical trials have advanced our understanding of the optimal treatment for multiple myeloma. The development of new combinations containing drugs such as thalidomide, bortezomib and lenalidomide is helping clinicians achieve complete remission and ...
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 www.ecancer.tv |
March 01, 2011
Prof Mathias Rummel talks about the history of bendamustine from its origins in 1960’s East Germany to the modern trials evaluating the use of bendamustine and rituximab to treat lymphoproliferative diseases.
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 www.ecancer.tv |
March 01, 2011
Prof Antonio Palumbo and Prof Vincent Rajkumar discuss some of the key research into myeloma that was presented at ASH 2010. This includes trials demonstrating that post transplant lenalidomide maintenance treatment dramatically improves progression free survival, a study comparing bortezomib ...
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 www.ecancer.tv |
February 23, 2011
Prof Anton Hagenbeek discusses the five and a half year results of the First-Line Indolent Trial (FIT) study. The randomised phase III FIT study evaluates the clinical benefits and safety of a single infusion of Zevalin (ibritumomab tiuxetan) in patients with previously untreated follicular ...
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