Cartagena is in the Murcia region of Spain. Cartagena is the main Seaport of the Murcia region. It has 214,000 inhabitants so it???s the second most populated municipality of the Region. Cartagena concentrates an artistic legacy that summarizes 2000 years of Spanish History, being inhabited by most great Mediterranean Empires that have conquered the Iberian Peninsula sometime. Cartagena is a very monumental city, with many archaeological sites and singular buildings, together with the charm of the sea and the typical bustle of a port city. Dirty and very polluted in the past (due to the nearby Refinery), the new reforms (like the initiative Cartagena, Port of CulturEs) and restorations have turned it into a a major tourist destinaton, and is a frequent disembarkation of numerous cruises. Its wide municipal territory also include part of the famous holiday resort La Manga del Mar Menor, part of the Mar Menor coast and several protected areas near the coast.